Elicit: Predicting Day-Case Arthroplasty Outcomes

Predicting Day-Case Arthroplasty Outcomes

Which patient factors best predict success/failure of day-case arthroplasty?

Increased age, female sex (OR 1.63-4.22), high ASA classification, and multiple comorbidities (OR up to 3.9) are the primary predictors of day-case arthroplasty failure.

Abstract

Day‐case arthroplasty outcomes are influenced by clear patient factors. Studies report that increased age—which in over 20 analyses shows odds ratios from 1.01 to 4.16—and female sex—with odds ratios from 1.63 to 4.22 in more than 15 investigations—predict lower same‐day discharge success. A higher body mass index (supported in 10+ studies) and non‐white race (noted in 5+ studies) similarly relate to reduced success. In addition, clinical indicators such as an ASA classification of III or IV and a comorbidity burden of three or more conditions consistently predict failure, with odds ratios up to 3.9 and highly significant p‐values. Other conditions, including hypertension, diabetes, cardiovascular disease, and chronic obstructive pulmonary disease, are also cited as contributing to poor day‐case outcomes. Although a couple of studies flag younger age (<40) as a potential risk factor, this finding remains inconsistent.

Methods

We analyzed 40 sources from an initial pool of 500, using 8 screening criteria. Each paper was reviewed for 6 key aspects that mattered most to the research question.

Paper search

Using your research question “Which patient factors best predict success/failure of day-case arthroplasty?”, we searched across over 126 million academic papers from the Semantic Scholar corpus. We retrieved the 500 papers most relevant to the query.

Screening

We screened in sources based on their abstracts that met these criteria:

We considered all screening questions together and made a holistic judgement about whether to screen in each paper.

Data extraction

Look in the methods section for explicit statements about study design. If the design is not clearly stated, carefully review the methodology description to determine the most appropriate classification. If uncertain, note “unclear” and provide a brief explanation.

Locate this information in the methods section. If criteria are not fully detailed, extract all available information. If partial or no criteria are provided, note “insufficient information” and quote any relevant text describing patient selection.

Locate this information in the patient characteristics section or baseline demographics table. If data is presented in multiple formats, prioritize mean/median values with standard deviation or confidence intervals. If specific factors are not fully reported, note which specific characteristics are missing.

Search results and discussion sections for explicit statements about discharge failure reasons. If reasons are not comprehensively listed, extract all available information. Ensure to differentiate between reasons for different types of arthroplasty (THA, TKA, mUKA) if such distinctions are made.

Prioritize information from multivariable regression analyses in the results section. If multiple analyses are present, extract results from the most comprehensive analysis. If predictive factors are not statistically analyzed, note “no statistical analysis of predictive factors” and extract any descriptive observations.

Locate this information in methods and results sections. If details vary between procedure types, create separate entries for each. If specific details are inconsistently or partially reported, extract all available information and note any limitations.

Results

Characteristics of Included Studies

Study Study Design Sample Size Setting Type Primary Outcome Definition Full text retrieved
Velichala et al., 2024 Retrospective 31,347 No mention found 30-day readmission after outpatient Total Knee Arthroplasty (TKA) No
Murrell et al., 2023 Retrospective, single-center 606 Single-center 24-hour discharge after elective hip/knee arthroplasty Yes
Keulen et al., 2020 Retrospective 525 No mention found Same-day discharge after outpatient hip/knee arthroplasty No
Foley et al., 2023 Retrospective analysis of prospectively collected data, single-center 466 Single-center Failure to achieve planned same-day discharge after Total Joint Arthroplasty (TJA) No
Sher et al., 2017 Retrospective, multi-center 120,847 Multi-center Same-day discharge and post-discharge complications after TJA No
Radtke et al., 2024 Retrospective, single-center 3,093 Single-center Failure to launch (discharge home) after scheduled same-day discharge TJA No
Danielsen et al., 2024 Prospective, multicentre cohort 6,142 Multicenter Day-case success after Total Hip Arthroplasty (THA), TKA, Medial Unicompartmental Knee Arthroplasty (mUKA) Yes
Gong et al., 2023 Retrospective, single-center 753 Single-center Reasons/risk factors for failed same-day discharge after TKA/THA No
Kort et al., 2017 Review 14 studies N/A Patient selection criteria for outpatient joint arthroplasty No
Jaibaji et al., 2020 Systematic review 6,519 N/A Complication/reoperation rates after outpatient arthroplasty No

Effects

Patient Demographics
Factor Effect Size Range Direction of Effect Number of Supporting Studies
Age (older) Odds Ratio (OR) 1.01–4.16, Relative Risk (RR) 1.44, OR 0.935 (inverse) Decreases same-day discharge success 20+
Female sex OR 1.63–4.22, RR 2.76 Decreases same-day discharge success 15+
Body Mass Index (higher) OR 1.06, OR 0.491 (inverse) Decreases same-day discharge success 10+
Non-white race OR 1.31–2.19, OR 0.456 (inverse) Decreases same-day discharge success 5+
Marital status (non-married) p=0.007 Decreases same-day discharge success 2
Younger age (<40) Increased risk in some studies Decreases same-day discharge success (inconsistently) 2

Key findings from these studies:

Clinical Characteristics
Factor Effect Size/Statistical Significance Direction of Effect Number of Supporting Studies
American Society of Anesthesiologists (ASA) class III/IV OR 1.42–3.9, OR 0.378 (inverse) Decreases same-day discharge success 15+
Comorbidity burden (≥3) OR 0.507 (inverse), p<0.001 Decreases same-day discharge success 10+
Hypertension OR 1.11–2.5, RR 2.5 Decreases same-day discharge success 8+
Diabetes OR 1.25–4.06 Decreases same-day discharge success 7+
Cardiovascular disease OR 1.67–12.06 Decreases same-day discharge success 6+
Chronic Obstructive Pulmonary Disease (COPD) OR 1.30–2.4 Decreases same-day discharge success 6+
Bleeding disorders OR 1.32–2.56 Decreases same-day discharge success 5+
Poor functional status p<0.001 Decreases same-day discharge success 4+
Preoperative opioid use OR 1.82, p=0.046 Decreases same-day discharge success 3+
Multiple allergies p<0.001 Decreases same-day discharge success 2+

Summary of findings:

Perioperative Factors
Factor Effect Size/Statistical Significance Direction of Effect Number of Supporting Studies
Later surgical start time OR 1.22–6.03, p<0.001 Decreases same-day discharge success 8+
General anesthesia (vs. spinal) p<0.0001 Decreases same-day discharge success 3+
Longer surgical/anesthesia duration OR 1.04, OR 4.28 per 30 min, p<0.001 Decreases same-day discharge success 10+
Higher blood loss p<0.0001 Decreases same-day discharge success 2+
Not ambulating on day of surgery OR 3.9–4.09, p<0.001 Decreases same-day discharge success 3+
Higher postoperative pain OR 1.93–5.85 Decreases same-day discharge success 2+

Key findings:

Success Rates and Risk Patterns

Overall Success Rates

Study Same-Day Discharge Success Rate Notes
Velichala et al., 2024 98.14% (1.86% readmission) Outpatient Total Knee Arthroplasty
Murrell et al., 2023 7.4% (<24h discharge) Elective hip/knee arthroplasty
Keulen et al., 2020 79% Outpatient hip/knee arthroplasty
Foley et al., 2023 99.7% (Ambulatory Surgery Center), 66.7% (hospital) Total Joint Arthroplasty
Danielsen et al., 2024 59–72% (eligible, by procedure) Total Hip Arthroplasty, Total Knee Arthroplasty, Medial Unicompartmental Knee Arthroplasty
Bayoumi et al., 2022 88% (Unicompartmental Knee Arthroplasty) Systematic review
French et al., 2024 85% (overall) Systematic review
Delfosse et al., 2024 97.2% High-volume center

Common Failure Patterns

Study Most Common Reasons for Failure Frequency/Proportion
Danielsen et al., 2024 Mobilization issues, prolonged spinal anesthesia, postoperative nausea and vomiting (PONV) 9–14% by reason
Gong et al., 2023 Failure to clear Physical Therapy, hypotension, urinary retention 33%, 20.5%, 16.9%
Bayoumi et al., 2022 Inability to mobilize, pain, nausea/vomiting 34%, 8%, 11%
Lieberman et al., 2021 Hypotension, delayed spinal anesthesia, nausea 24.4%, 24.4%, 11.1%
Vermaak et al., 2024 Mobilization, nausea/vomiting, social issues 16, 14, 11 cases
Delfosse et al., 2024 Urinary retention, orthostatic hypotension, pain 28.6%, 28.6%, 14.3%

Risk Stratification Models

Study Model/Tool Predictive Value Notes
Meneghini et al., 2017 Outpatient Arthroplasty Risk Assessment (OARA) score OR 2.0–2.7 for early discharge More predictive than American Society of Anesthesiologists (ASA)/Charlson Comorbidity Index (CCI)
Crawford et al., 2022 OARA score Accurate for same-day discharge, poor for failure May be too restrictive
Goltz et al., 2021 13-variable model Area Under the Curve (AUC) 0.762 Shoulder arthroplasty
Turcotte et al., 2021 Logistic regression AUC 0.773 Total Knee Arthroplasty
Wei et al., 2021 Artificial Neural Network (ANN) model AUC 0.801 Total Knee Arthroplasty

References

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  4. A. Sher et al., (2017). Predictors of Same-Day Discharge in Primary Total Joint Arthroplasty Patients and Risk Factors for Post-Discharge Complications. Journal of Arthroplasty
  5. Logan Radtke et al., (2024). Outpatient Total Joint Arthroplasty at a High-Volume Academic Center: An Analysis of Failure to Launch. Journal of Arthroplasty
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Report

Version: August 7, 2025 11:20 AM
Status: Gather sources
Details: 500 sources found