Elicit: Predicting Day-Case Arthroplasty Outcomes
Predicting Day-Case Arthroplasty Outcomes
Which patient factors best predict success/failure of day-case arthroplasty?
Increased age, female sex (OR 1.63-4.22), high ASA classification, and multiple comorbidities (OR up to 3.9) are the primary predictors of day-case arthroplasty failure.
Abstract
Day‐case arthroplasty outcomes are influenced by clear patient factors. Studies report that increased age—which in over 20 analyses shows odds ratios from 1.01 to 4.16—and female sex—with odds ratios from 1.63 to 4.22 in more than 15 investigations—predict lower same‐day discharge success. A higher body mass index (supported in 10+ studies) and non‐white race (noted in 5+ studies) similarly relate to reduced success. In addition, clinical indicators such as an ASA classification of III or IV and a comorbidity burden of three or more conditions consistently predict failure, with odds ratios up to 3.9 and highly significant p‐values. Other conditions, including hypertension, diabetes, cardiovascular disease, and chronic obstructive pulmonary disease, are also cited as contributing to poor day‐case outcomes. Although a couple of studies flag younger age (<40) as a potential risk factor, this finding remains inconsistent.
Methods
We analyzed 40 sources from an initial pool of 500, using 8 screening criteria. Each paper was reviewed for 6 key aspects that mattered most to the research question. More on methods
Paper search
Using your research question "Which patient factors best predict success/failure of day-case arthroplasty?", we searched across over 126 million academic papers from the Semantic Scholar corpus. We retrieved the 500 papers most relevant to the query.
Screening
We screened in sources based on their abstracts that met these criteria:
- Study Setting: Does the study investigate outpatient/day-case/ambulatory arthroplasty procedures?
- Patient Population - Age: Does the study include only adult patients (≥18 years)?
- Procedure Type: Does the study examine primary (non-revision) hip, knee, shoulder, or ankle arthroplasty?
- Clinical Context: Does the study examine planned elective procedures (not emergency or trauma-related cases)?
- Predictive Factors: Does the study analyze patient-related predictive factors (such as age, BMI, comorbidities, or social support)?
- Outcome Measures: Does the study report specific outcomes related to success/failure of day-case surgery (such as same-day discharge, unplanned overnight stays, or 30-day readmissions)?
- Study Design: Is the study design either a prospective/retrospective cohort study, case-control study, RCT, or systematic review with 10 or more patients?
- Study Focus: Does the study include patient-related factors (not exclusively focusing on surgical technique, anesthetic protocol, or hospital/surgeon factors)?
We considered all screening questions together and made a holistic judgement about whether to screen in each paper.
Data extraction
We asked a large language model to extract each data column below from each paper. We gave the model the extraction instructions shown below for each column.
- Study Design:
- Patient Selection Criteria:
- Patient Demographic and Clinical Factors:
- Reasons for Same-Day Discharge Failure:
- Predictive Factors for Same-Day Discharge Success:
- Surgical Procedure Details:
Results
Characteristics of Included Studies
| Study | Study Design | Sample Size | Setting Type | Primary Outcome Definition | Full text retrieved |
|---|---|---|---|---|---|
| Velichala et al., 2024 | Retrospective | 31,347 | No mention found | 30-day readmission after outpatient Total Knee Arthroplasty (TKA) | No |
| Murrell et al., 2023 | Retrospective, single-center | 606 | Single-center | 24-hour discharge after elective hip/knee arthroplasty | Yes |
| Keulen et al., 2020 | Retrospective | 525 | No mention found | Same-day discharge after outpatient hip/knee arthroplasty | No |
| Foley et al., 2023 | Retrospective analysis of prospectively collected data, single-center | 466 | Single-center | Failure to achieve planned same-day discharge after Total Joint Arthroplasty (TJA) | No |
| Sher et al., 2017 | Retrospective, multi-center | 120,847 | Multi-center | Same-day discharge and post-discharge complications after TJA | No |
| Danielsen et al., 2024 | Prospective, multicentre cohort | 6,142 | Multicenter | Day-case success after Total Hip Arthroplasty (THA), TKA, Medial Unicompartmental Knee Arthroplasty (mUKA) | Yes |
| Gong et al., 2023 | Retrospective, single-center | 753 | Single-center | Reasons/risk factors for failed same-day discharge after TKA/THA | No |
| Kort et al., 2017 | Review | 14 studies | N/A | Patient selection criteria for outpatient joint arthroplasty | No |
| Jaibaji et al., 2020 | Systematic review | 6,519 | N/A | Complication/reoperation rates after outpatient arthroplasty | No |
Patient Demographics
- Age: Older age (OR: 1.01–4.16)
- Female sex: OR 1.63–4.22
- Body Mass Index: OR 1.06
- Non-white race: OR 1.31–2.19
- Marital status: p=0.007 (non-married)
- Younger age (<40): Reported as a potential risk factor but inconsistent.
Common Failure Patterns
| Study | Most Common Reasons for Failure | Frequency/Proportion |
|---|---|---|
| Danielsen et al., 2024 | Mobilization issues, prolonged spinal anesthesia, postoperative nausea and vomiting (PONV) | 9–14% by reason |
| Gong et al., 2023 | Failure to clear Physical Therapy, hypotension, urinary retention | 33%, 20.5%, 16.9% |
| Bayoumi et al., 2022 | Inability to mobilize, pain, nausea/vomiting | 34%, 8%, 11% |
| Delfosse et al., 2024 | Urinary retention, orthostatic hypotension, pain | 28.6%, 28.6%, 14.3% |
Overall Success Rates
| Study | Same-Day Discharge Success Rate | Notes |
|---|---|---|
| Velichala et al., 2024 | 98.14% (1.86% readmission) | Outpatient Total Knee Arthroplasty |
| Murrell et al., 2023 | 7.4% (<24h discharge) | Elective hip/knee arthroplasty |
| Keulen et al., 2020 | 79% | Outpatient hip/knee arthroplasty |
| Foley et al., 2023 | 99.7% (Ambulatory Surgery Center), 66.7% (hospital) | Total Joint Arthroplasty |
References
- James Murrell et al. (2023). Identifying Preoperative Predictors for 24-Hour Discharge After Elective Hip and Knee Arthroplasties.
- M. Keulen et al. (2020). Predictors of (Un)successful Same-Day Discharge in Selected Patients Following Outpatient Hip and Knee Arthroplasty.