Elicit: Predicting Day-Case Arthroplasty Outcomes

Predicting Day-Case Arthroplasty Outcomes

Which patient factors best predict success/failure of day-case arthroplasty?

Increased age, female sex (OR 1.63-4.22), high ASA classification, and multiple comorbidities (OR up to 3.9) are the primary predictors of day-case arthroplasty failure.

Abstract

Day‐case arthroplasty outcomes are influenced by clear patient factors. Studies report that increased age—which in over 20 analyses shows odds ratios from 1.01 to 4.16—and female sex—with odds ratios from 1.63 to 4.22 in more than 15 investigations—predict lower same‐day discharge success. A higher body mass index (supported in 10+ studies) and non‐white race (noted in 5+ studies) similarly relate to reduced success. In addition, clinical indicators such as an ASA classification of III or IV and a comorbidity burden of three or more conditions consistently predict failure, with odds ratios up to 3.9 and highly significant p‐values. Other conditions, including hypertension, diabetes, cardiovascular disease, and chronic obstructive pulmonary disease, are also cited as contributing to poor day‐case outcomes. Although a couple of studies flag younger age (<40) as a potential risk factor, this finding remains inconsistent.

Methods

We analyzed 40 sources from an initial pool of 500, using 8 screening criteria. Each paper was reviewed for 6 key aspects that mattered most to the research question.

Paper search

Using your research question “Which patient factors best predict success/failure of day-case arthroplasty?”, we searched across over 126 million academic papers from the Semantic Scholar corpus. We retrieved the 500 papers most relevant to the query.

Screening

We screened in sources based on their abstracts that met these criteria:

We considered all screening questions together for holistic judgment.

Data extraction

We asked a large language model to extract each data column below from each paper:

Results

Characteristics of Included Studies

Study Study Design Sample Size Setting Type Primary Outcome Definition Full text retrieved
Velichala et al., 2024 Retrospective 31,347 No mention found 30-day readmission after outpatient Total Knee Arthroplasty (TKA) No
Murrell et al., 2023 Retrospective, single-center 606 Single-center 24-hour discharge after elective hip/knee arthroplasty Yes
...
Danielsen et al., 2024 Prospective, multicentre cohort 6,142 Multicenter Day-case success after Total Hip Arthroplasty (THA), TKA, Medial Unicompartmental Knee Arthroplasty (mUKA) Yes

Patient Demographics

Factor Effect Size Range Direction of Effect Number of Supporting Studies
Age (older) Odds Ratio (OR) 1.01–4.16 Decreases same-day discharge success 20+
Female sex OR 1.63–4.22 Decreases same-day discharge success 15+
...
Younger age (<40) Increased risk in some studies Decreases same-day discharge success (inconsistently) 2

Common Failure Patterns

Study Most Common Reasons for Failure Frequency/Proportion
Danielsen et al., 2024 Mobilization issues, postoperative nausea and vomiting (PONV) 9–14% by reason
...
Bayoumi et al., 2022 Inability to mobilize, pain, nausea/vomiting 34%, 8%, 11%

Risk Stratification Models

Study Model/Tool Predictive Value Notes
Meneghini et al., 2017 Outpatient Arthroplasty Risk Assessment (OARA) score OR 2.0–2.7 for early discharge More predictive than ASA/CCI
...

References

  1. James Murrell, N. Khadabadi, Thomas Moores, Fahad Hossain. (2023). Identifying Preoperative Predictors for 24-Hour Discharge After Elective Hip and Knee Arthroplasties. Cureus
  2. M. Keulen et al. (2020). Predictors of (Un)successful Same-Day Discharge in Selected Patients Following Outpatient Hip and Knee Arthroplasty. Journal of Arthroplasty
  3. Ehab M. Nazzal, Fritz Steuer, Matthew Como, Ryan Gilbert, S. Adida. (2025). Predictors of Failing Same-Day Discharge after Shoulder Arthroplasty: Developing a Model to Improve Outcomes and Reduce Healthcare Cost. Journal of shoulder and elbow surgery

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(Additional references omitted for brevity.)